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gsea-pathway-analyzer

// Gene Set Enrichment Analysis skill for functional annotation and pathway interpretation

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updated:March 4, 2026
SKILL.mdreadonly
SKILL.md Frontmatter
namegsea-pathway-analyzer
descriptionGene Set Enrichment Analysis skill for functional annotation and pathway interpretation
allowed-toolsRead,Write,Glob,Grep,Edit,WebFetch,WebSearch,Bash
metadata[object Object]

GSEA Pathway Analyzer Skill

Purpose

Enable Gene Set Enrichment Analysis for functional annotation and pathway interpretation.

Capabilities

  • Preranked GSEA execution
  • Gene ontology enrichment
  • KEGG/Reactome pathway analysis
  • Custom gene set support
  • Leading edge analysis
  • Publication-ready visualizations

Usage Guidelines

  • Rank genes appropriately for analysis type
  • Select relevant gene set collections
  • Apply multiple testing correction
  • Identify leading edge genes for interpretation
  • Generate clear visualizations
  • Document gene set versions

Dependencies

  • GSEA
  • clusterProfiler
  • g:Profiler
  • Enrichr

Process Integration

  • RNA-seq Differential Expression Analysis (rnaseq-differential-expression)
  • Single-Cell RNA-seq Analysis (scrnaseq-analysis)
  • Multi-Omics Data Integration (multi-omics-integration)